Iridium catalyzed alkylation of 2′-hydroxyacetophenone with alcohols under thermal or microwave conditions
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چکیده
منابع مشابه
Room temperature and solvent-free iridium-catalyzed selective alkylation of anilines with alcohols.
A bidentate iridium NHC-phosphine complex has been developed and applied to the N-monoalkylation of aromatic amines with a wide range of primary alcohols and to the N-heterocyclization of amino alcohols. This reaction resulted in high isolated product yields, even at room temperature and under solvent-free conditions.
متن کاملDirect N-alkylation of amino-azoles with alcohols catalyzed by an iridium complex/base system.
The direct and regioselective N-alkylation of amino-azoles to the corresponding 2-N-(alkylamino)azoles using various alcohols as alkylating agents with good to excellent yields has been accomplished by an iridium complex/base system.
متن کاملAlkylation of active methylene compounds with alcohols catalyzed by an iridium complex.
Base-free catalytic alpha-alkylation of active methylene compounds with primary alcohols was successfully achieved using an [IrCl(cod)](2) complex in the presence of PPh(3) to afford the corresponding saturated alpha-alkylated products in good yields.
متن کاملIridium-catalysed amine alkylation with alcohols in water.
Amines have been directly alkylated with alcohols using 1 mol% [Cp*IrI(2)](2) catalyst in water in the absence of base or other additives.
متن کاملPalladium catalyzed N-alkylation of amines with alcohols
An iron oxide immobilized palladium catalyst was prepared for the N-alkylation of amines with alcohols under base and organic ligand free conditions. Applying the optimized reaction conditions, the coupling reactions of amines and alcohols with various structures could be realized with up to 99% isolated yields. The catalysts were studied by XRD, BET, and XPS and the mechanism was studied by DF...
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ژورنال
عنوان ژورنال: Tetrahedron Letters
سال: 2017
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2017.10.024